Residual Solvents and non-traditional drug products!

According to todays on-line USP, General Chapters: <467> RESIDUAL SOLVENTS, Water-Soluble articles, Test Stock Solution - “Transfer about 250 mg of the article under test, accurately weighed, to a 25 -mL volumetric flask, dissolve in and dilute with water to volume and mix“. In Water-Insoluble articles, Test Stock Solution - “Transfer about 250 mg of the article under test, accurately weighed, to a 25 -mL volumetric flask, dissolve in and dilute with dimethylformamide to volume and mix“.